{"id":26,"date":"2016-06-20T14:13:47","date_gmt":"2016-06-20T14:13:47","guid":{"rendered":"http:\/\/madamczyk.ch.pw.edu.pl\/?page_id=26"},"modified":"2025-08-12T21:39:37","modified_gmt":"2025-08-12T21:39:37","slug":"contact","status":"publish","type":"page","link":"https:\/\/madamczyk.ch.pw.edu.pl\/index.php\/contact\/","title":{"rendered":"Contact us"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Contact&#8221; _builder_version=&#8221;4.25.2&#8243; _module_preset=&#8221;default&#8221; background_enable_color=&#8221;off&#8221; custom_padding=&#8221;0px||4px|||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{%22gcid-b6c4f12c-f25d-4f61-9fb1-6e96404634cd%22:%91%22background_color%22%93}&#8221;][et_pb_row _builder_version=&#8221;4.25.2&#8243; _module_preset=&#8221;default&#8221; max_width=&#8221;1320px&#8221; custom_padding=&#8221;||4px|||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.25.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_heading title=&#8221;Contact Us&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;b62ad52a-c7ac-4f07-9bf0-6c1aa5a2c0dc&#8221; title_level=&#8221;h4&#8243; title_font_size=&#8221;31px&#8221; custom_margin=&#8221;||10px||false|false&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;][\/et_pb_heading][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_2&#8243; _builder_version=&#8221;4.25.2&#8243; _module_preset=&#8221;default&#8221; max_width=&#8221;1320px&#8221; custom_padding=&#8221;3px|||||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.25.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;e133361a-9514-4c13-a6e3-17e30abefbff&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<h6>Ma\u0142gorzata Adamczyk\u2019s office is located on the 1st Floor of the Chemical Technology Buiding in Room 103a<\/h6>\n<p>[\/et_pb_text][et_pb_blurb title=&#8221;Call&#8221; use_icon=&#8221;on&#8221; font_icon=&#8221;&#xf10b;||fa||900&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;aa080900-7e66-4a6a-aa5d-eb029d322c0b&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; header_font_size=&#8221;20px&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p>+48 22 234 7677<\/p>\n<p>[\/et_pb_blurb][et_pb_blurb title=&#8221;Email&#8221; use_icon=&#8221;on&#8221; font_icon=&#8221;&#xf658;||fa||900&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;aa080900-7e66-4a6a-aa5d-eb029d322c0b&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; header_font_size=&#8221;20px&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p><a href=\"mailto:malgorzata_adamczyk@pw.edu.pl\">malgorzata_adamczyk@pw.edu.pl<\/a><\/p>\n<p>[\/et_pb_blurb][et_pb_contact_form captcha=&#8221;off&#8221; email=&#8221;malgorzata_adamczyk@pw.edu.pl&#8221; submit_button_text=&#8221;Send&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;7834d555-ecf3-4899-9a36-385c5dcb0505&#8243; title_level=&#8221;h3&#8243; button_text_color=&#8221;#000000&#8243; global_colors_info=&#8221;{%22gcid-b6c4f12c-f25d-4f61-9fb1-6e96404634cd%22:%91%22background_color%22%93,%22gcid-2ebbc52c-9ee6-4712-a077-fcaec9b98540%22:%91%22button_bg_color%22%93}&#8221;][et_pb_contact_field field_id=&#8221;Name&#8221; field_title=&#8221;Name&#8221; fullwidth_field=&#8221;on&#8221; _builder_version=&#8221;4.25.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; button_text_size__hover_enabled=&#8221;off&#8221; button_one_text_size__hover_enabled=&#8221;off&#8221; button_two_text_size__hover_enabled=&#8221;off&#8221; button_text_color__hover_enabled=&#8221;off&#8221; button_one_text_color__hover_enabled=&#8221;off&#8221; button_two_text_color__hover_enabled=&#8221;off&#8221; button_border_width__hover_enabled=&#8221;off&#8221; 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button_two_border_color__hover_enabled=&#8221;off&#8221; button_border_radius__hover_enabled=&#8221;off&#8221; button_one_border_radius__hover_enabled=&#8221;off&#8221; button_two_border_radius__hover_enabled=&#8221;off&#8221; button_letter_spacing__hover_enabled=&#8221;off&#8221; button_one_letter_spacing__hover_enabled=&#8221;off&#8221; button_two_letter_spacing__hover_enabled=&#8221;off&#8221; button_bg_color__hover_enabled=&#8221;off&#8221; button_one_bg_color__hover_enabled=&#8221;off&#8221; button_two_bg_color__hover_enabled=&#8221;off&#8221;][\/et_pb_contact_field][\/et_pb_contact_form][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.25.2&#8243; _module_preset=&#8221;b51bb323-ae7c-4231-9e20-99a8f199b9e8&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_code _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;-97px|||||&#8221; custom_padding=&#8221;34px|||||&#8221; global_colors_info=&#8221;{}&#8221;]<iframe src=\"https:\/\/www.google.com\/maps\/embed?pb=!1m18!1m12!1m3!1d1987.8660732375092!2d21.00622265579095!3d52.221653807152045!2m3!1f0!2f0!3f0!3m2!1i1024!2i768!4f13.1!3m3!1m2!1s0x471ecd096bc649c1%3A0xf9eb05c6625aa386!2sGmach%20Technologii%20Chemicznej%20Politechniki%20Warszawskiej!5e1!3m2!1spl!2spl!4v1751492373021!5m2!1spl!2spl\" width=\"600\" height=\"450\" style=\"border:0;\" allowfullscreen=\"\" loading=\"lazy\" referrerpolicy=\"no-referrer-when-downgrade\"><\/iframe>[\/et_pb_code][et_pb_blurb title=&#8221;Office&#8221; use_icon=&#8221;on&#8221; font_icon=&#8221;&#xf276;||fa||900&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;aa080900-7e66-4a6a-aa5d-eb029d322c0b&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Faculty of Chemistry<br \/>Department of Drug Technology and Biotechnology<br \/>Warsaw University of Technology<br \/>ul. Noakowskiego 3<br \/>00-664 Warsaw, Poland<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#006d77&#8243; custom_padding=&#8221;0px||0px||false|false&#8221; saved_tabs=&#8221;all&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.25.2&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;-15px|auto||auto||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.25.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_heading title=&#8221;OFFER FOR a PhD STUDENT in IDUB project Excellence Initiative Research University WUT, Warsaw (2025)&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;bd9b0806-0f5a-4caf-8370-654735f33f55&#8243; title_text_color=&#8221;#FFFFFF&#8221; custom_margin=&#8221;||10px||false|false&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; title_font_size=&#8221;25px&#8221; sticky_enabled=&#8221;0&#8243;][\/et_pb_heading][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;a198dc3c-00bc-4517-99cd-75794b6c13e1&#8243; text_text_color=&#8221;#FFFFFF&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><span style=\"font-size: large;\">\u201cDeveloping a synthetic genetically modified host for biosynthesis of biodegradable and thermoplastic polymers&#8221;<\/span><\/p>\n<p>\u00a0We are looking for a qualified PhD student to join our dynamic research team to carry out advanced research in the field of applied microbiology, synthetic biology and biotechnology of biopolymers derived from genetically modified yeast cells.<\/p>\n<p>The person offered a PhD position will be responsible for carrying out the research project, writing scientific publications and collaborating with other team members.<\/p>\n<p>[\/et_pb_text][et_pb_heading title=&#8221;PHD position Offer Description&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;bd9b0806-0f5a-4caf-8370-654735f33f55&#8243; title_text_color=&#8221;#FFFFFF&#8221; custom_margin=&#8221;||10px||false|false&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; title_font_size=&#8221;25px&#8221; sticky_enabled=&#8221;0&#8243;][\/et_pb_heading][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;a198dc3c-00bc-4517-99cd-75794b6c13e1&#8243; text_text_color=&#8221;#FFFFFF&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>The candidate should have a MSc degree in chemistry, biology, or related field. The candidate is expected to have experience in at least one of the research directions listed below:<\/p>\n<p>&#8211; molecular biology, genome editing techniques, DNA\/RNA manipulation<\/p>\n<p>&#8211; proven experience at working with bacteria or yeast<\/p>\n<p>&#8211; analysis of natural polymers, e.g. chromatographic analysis<\/p>\n<p>&#8211; extraction of polymers from biological material<\/p>\n<p>His\/her scientific achievements should be documented by the authorship of papers\u00a0 related to the profile of the announced research position. Capability of leading independent research activity is a necessary requirement.<\/p>\n<p>The project will be focused on obtaining genetically modified strains of S.cerevisiae\u00a0 and their characterization. Genetic manipulations will require to design and prepare constructs for \u00a0\u00a0CRISP\/Cas genome editing of\u00a0<em>S.cerevisiae.<\/em>\u00a0Genetic manipulations are aimed at obtaining a strain capable of simultaneouse biosynthesis of mixed\u00a0 PHB\/PLA (poly((R-3 hydroxybutyrate\/polylactide) polymers. As part of the research conducted so far, the project leader&#8217;s team has developed a strain with a favorable metabolic profile, which will serve as the starting point for genetic manipulation and for the production of the polymers. The effects of genome editing will be verified at the level of transcription using real-time PCR, at the level of metabolism by determining concentration of intracellular metabolites and in the culture media, as well as at the level of activity of selected enzymes, in the synthetic pathways as well as their cellular levels using the Western Blot\u00a0immunodetection method. In the case of the most promising strains, quantitative tests of the synthesis of polylactide and hydroxybutyrate will be carried out, as well as optimization of polymer production efficiency using a laboratory bioreactor. Extraction and characterization of polymers in terms of their composition will be carried out using chromatographic methods and MALDI-TOF mass spectrometry. Optimization of the polymer extraction process from\u00a0<em>S.cerevisiae<\/em> will be a key step in the project, that will be followed by evaluation of the strategy in the design of a synthetic hybrid microorganism as an efficient polymers producer. The project will be caried out in a few interactions to obtain the optimal solution.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ma\u0142gorzata Adamczyk\u2019s office is located on the 1st Floor of the Chemical Technology Buiding in Room 103a+48 22 234 7677malgorzata_adamczyk@pw.edu.plFaculty of ChemistryDepartment of Drug Technology and BiotechnologyWarsaw University of Technologyul. Noakowskiego 300-664 Warsaw, Poland\u201cDeveloping a synthetic genetically modified host for biosynthesis of biodegradable and thermoplastic polymers&#8221; \u00a0We are looking for a qualified PhD student to [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"We are interested in motivated undergraduate students (Bachelor\/Master), graduate students (PhD students) to join the group.\nIf you want further information please email madamczyk@ch.pw.edu.pl\n\n<strong>OFERTA DLA DOKTORANT\u00d3W w projekcie OPUS (2016-2019) <\/strong>\n<p style=\"text-align: right;\">\" Wp\u0142yw mobilnych element\u00f3w na metabolizm bakterii. Dynamiczne polimery alfahelikalnych <img class=\"wp-image-140 alignright\" src=\"http:\/\/madamczyk.ch.pw.edu.pl\/wp-content\/uploads\/2016\/06\/NCN.png\" alt=\"NCN\" width=\"157\" height=\"49\" \/>bia\u0142ek plazmidowych typu Kfr w organizacji prokariotycznego \"wrzeciona mitotycznego\"<\/p>\n<p style=\"text-align: justify;\">Oferta dotyczy bada\u0144 w ramach pracy doktorskiej jak r\u00f3wnie\u017c wolontariatu studenckiego. Pozycja na stanowisku doktoranta jest finansowana przez Narodowe Centrum Nauki. Badania dotycz\u0105 wyja\u015bnienia roli bia\u0142ka Kfr w biologii plazmid\u00f3w, kt\u00f3re maj\u0105 szeroki zakres gospodarzy. Co to znaczy? To znaczy, \u017ce tego typu plazmidy s\u0105 wsz\u0119dobylskie i mog\u0105 z powodzeniem ulega\u0107 replikacji w r\u00f3\u017cnych klasach bakterii. Z jednej strony czyni to z nich cenne narz\u0119dzie biotechnologiczne, a z drugiej k\u0142opotliwy mobilny element genetyczny, kt\u00f3ry jest odpowiedzialny za szerzenie si\u0119 lekooporno\u015bci w\u015br\u00f3d odleg\u0142ych filogenetycznie gatunk\u00f3w bakterii izolowanych z gleby, \u015brodowiska wodnego i od pacjent\u00f3w szpitali. Plazmidy te s\u0105 bardzo stabilne, czyli bez presji selekcyjnej (np. dodania antybiotyku do hodowli) utrzymuj\u0105 si\u0119 w kom\u00f3rkach przez wiele generacji. KfrA, bierze udzia\u0142 w stabilizacji cz\u0105steczek plazmidowego DNA. Badania s\u0105 w toku, gdy\u017c chcemy zrozumie\u0107 na czym dok\u0142adnie polega udzia\u0142 Kfr w tym procesie. Jednym z podej\u015b\u0107 badawczych do zagadnienia jest przeprowadzenie analizy strukturalnej bia\u0142ka, a KfrA ma bardzo ciekaw\u0105 struktur\u0119, poniewa\u017c wygl\u0105da jak lina okr\u0119towa. <a href=\"http:\/\/madamczyk.ch.pw.edu.pl\/wp-content\/uploads\/2016\/06\/lina-okretowa.bmp\"><img class=\"wp-image-142 aligncenter\" src=\"http:\/\/madamczyk.ch.pw.edu.pl\/wp-content\/uploads\/2016\/06\/lina-okretowa.bmp\" alt=\"lina okretowa\" width=\"367\" height=\"114\" \/><\/a><\/p>\n<p style=\"text-align: justify;\">Projekt, kt\u00f3rym chc\u0119 pa\u0144stwa zainteresowa\u0107, jest \u00a0realizowany w konsorcjum, tak wi\u0119c nie jeste\u015bmy sami. Cz\u0119\u015b\u0107 zada\u0144 badawczych dotyczy analizy mikroskopowej i lokalizacji bia\u0142ek w kom\u00f3rce przy pomocy znacznik\u00f3w fluorescencyjnych, analizy TEM (mikroskopii elektronowej, bada\u0144 oddzia\u0142ywania Kfr z innymi bia\u0142kami np. przy pomocy termoforezy)\u00a0oraz\u00a0analizy metabolomu bakterii, kt\u00f3re nios\u0105 plazmidy ze zmutowanymi genami <em>kfr<\/em>. Aby przeprowadzi\u0107 dok\u0142adn\u0105 charakterystyk\u0119 bia\u0142ek Kfr konieczne jest r\u00f3wnie\u017c zaprojektowanie mutant\u00f3w w domenach funkcyjnych tego bia\u0142ka. Przeprowadzimy analiz\u0119 wi\u0105zania zmutowanych form Kfr do oligonukleotyd\u00f3w immobilizowanych na sensorze i wyznaczymy sta\u0142e wi\u0105zania przy pomocy wagi kwarcowej.<\/p>\n<p style=\"text-align: justify;\">Podsumowuj\u0105c, praca dotyczy: prowadzenia hodowli bakteryjnych, manipulacji DNA, PCR, klonowania, nadprodukcji i oczyszczania bia\u0142ek, obrazowania bia\u0142ek oraz badania oddzia\u0142ywa\u0144 <em>in vivo<\/em> oraz <em>in vitro<\/em>, przy u\u017cyciu najnowszych technik biofizycznych, na koniec........metabolomiki oraz analizy modyfikacji bia\u0142ka metod\u0105 spektrometrii mas. Nie wszystkie zadania b\u0119d\u0105 realizowane na terenie Wydzia\u0142u Chemicznego Politechniki Warszawskiej. Prace ju\u017c trwaj\u0105.<\/p>\nJe\u015bli s\u0105 pa\u0144stwo zainteresowani ofert\u0105, to poprosz\u0119 o przes\u0142anie CV.\n\nProsz\u0119 pisa\u0107 do mnie, je\u015bli nasun\u0105 si\u0119 Pa\u0144stwu nowe pytania.","_et_gb_content_width":"","footnotes":""},"class_list":["post-26","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/madamczyk.ch.pw.edu.pl\/index.php\/wp-json\/wp\/v2\/pages\/26","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/madamczyk.ch.pw.edu.pl\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/madamczyk.ch.pw.edu.pl\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/madamczyk.ch.pw.edu.pl\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/madamczyk.ch.pw.edu.pl\/index.php\/wp-json\/wp\/v2\/comments?post=26"}],"version-history":[{"count":27,"href":"https:\/\/madamczyk.ch.pw.edu.pl\/index.php\/wp-json\/wp\/v2\/pages\/26\/revisions"}],"predecessor-version":[{"id":679,"href":"https:\/\/madamczyk.ch.pw.edu.pl\/index.php\/wp-json\/wp\/v2\/pages\/26\/revisions\/679"}],"wp:attachment":[{"href":"https:\/\/madamczyk.ch.pw.edu.pl\/index.php\/wp-json\/wp\/v2\/media?parent=26"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}